R 450.00



One 30mg tablet per day every morning directly after breakfast. Sibutramine causes insomnia. Therefore, it should not be used at night.

Sibutralean Slim tablets are manufactured as a big tablet with a breaker in the middle. As a result, we highly recommend that new users start with 1/2 tablet and then work their way up to a full tablet. Sibutralean has been known for causing severe increases in heart rate. In addition it also causes feelings of anxiety. If you are not use to these kinds of side effects it is recommended that you start on 1/2 tab.


Sibutramine hydrochloride is a selective serotonin and noradrenaline re-uptake inhibitor. Obesity management is the main medical use of sibutramine. This is not a rapid acting drug. In other words it works rather slow and in a safe manner. This leads to a steady reduction in fat mass. Longer-term results can be maintained . This drug is most effective in conjunction with a low calorie diet and training program.

Sibutralean reduces body fat via two very distinct and effective mechanisms. Firstly, it suppresses the appetite. Studies have shown people decrease their calorie intake with as much as 1300 calories a day. Secondly, Sibutralean stimulates metabolism and daily caloric expenditure. A single tablet of 30 mg sibutramine has shown an increase in basal metabolic rate by up to 30%. This increase in metabolic rate usually lasts up to six hours from taking the capsule.

Sibutramine has a thermogenic action that happens in the adrenergic system. This happens mainly through the indirect support of beta 3-receptor activation. With subutralen we mainly see strong increases in brown adipose tissue thermogenesis (BAT). This increases the body temperature by 0.5 to 1 degree Celsius. As soon as the body temperature increases it is a clear indication that thermogenesis has been triggered. This means that burning is now taking place.

Clinical trials have shown that sibutramine works remarkably well with obese patients. The trials found that sibutramine also had significant improvements in serum triglyceride and HDL cholesterol levels. Patients entered into the clinical trials were obese. As a result their HDL cholesterol levels were extremely high when they started the clinical trials. For someone who is not obese the improvements in serum triglyceride and HDL cholesterol levels might not be as significant.

Side Effects

The most common side effect with sibutramine is an increase in blood pressure. For this reason patients with high blood pressure and cardiovascular problems should not be using this product. Other common side effects include dry mouth, sleeplessness, irritability, back pain, stomach upset and constipation. The side effects Sibutramine causes usually subsides in the patient as they becomes accustomed to usage. Patients who are using any form of antidepressant should also not use this product. The drug interactions between sibutramine hydrochloride and antidepressants have shown to be a very negative one.

Water Intake

After taking the 30 mg tablet of sibutramine in the morning you will get instantly very thirsty. Consequently, make sure you consume as much water as possible when this thirst sets in. Some people fight this thirst. This reduces the positive effects of sibutramine. As you increase your water intake sibutramine better activated. Fat burning results are more increased. Fighting the thirst without water consumption decreases the appetite suppressing characteristics. People who consumed a lot of water get better results. Therefore, without water uptake you get very hungry late afternoon. When the product wears off you then defeat the object by consuming large amounts of food. With the increase of water late afternoon hunger is not an issue.

Sibutramine affects chemicals in the brain that affect weight maintenance.

Sibutramine is used together with diet and exercise to treat obesity that may be related to diabetes, high cholesterol, or high blood pressure.

Sibutramine may also be used for other purposes not listed in this medication guide.

Do not use sibutramine if you have taken an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) in the last 14 days. Serious, life threatening side effects can occur if you use sibutramine before the MAO inhibitor has cleared from your body.

You should not take sibutramine if you are allergic to it, or if you have severe or uncontrolled high blood pressure, an eating disorder (anorexia or bulimia), if you are taking stimulant diet pills, or if you have a history of coronary artery disease, stroke, or heart disease.

Before taking sibutramine, tell your doctor if you have glaucoma, high blood pressure, liver or kidney disease, depression, underactive thyroid, seizures, a bleeding disorder, a history of gallstones, or if you are older than 65 or younger than 16.

Tell your doctor about all prescription and over-the-counter medications you use, especially antidepressants, cold or allergy medication, narcotic pain medicine, or migraine headache medicines.

Tell your doctor if you do not lose at least 4 pounds after taking the medication for 4 weeks along with a low calorie diet.

Do not use sibutramine if you have taken an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) in the last 14 days. Serious, life threatening side effects can occur if you use sibutramine before the MAO inhibitor has cleared from your body.

You should not take this medication if you are allergic to sibutramine, or if you have:

  • severe or uncontrolled hypertension (high blood pressure);
  • an eating disorder (anorexia or bulimia);
  • a history of coronary artery disease (atherosclerosis);
  • a history of heart disease (congestive heart failure, heart rhythm disorder);
  • a history of heart attack or stroke; or
  • if you are taking stimulant diet pills.

If you have any of these other conditions, you may need a sibutramine dose adjustment or special tests:

  • glaucoma;
  • high blood pressure;
  • liver disease;
  • kidney disease;
  • depression;
  • underactive thyroid;
  • epilepsy or seizure disorder;
  • a bleeding or blood clotting disorder;
  • a history of gallstones; or
  • if you are older than 65 or younger than 16.

FDA pregnancy category C. It is not known whether sibutramine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using sibutramine.

It is not known whether sibutramine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give this medication to anyone younger than 16 years old.

What is Phentermine

The weight loss drug Phentermine is an appetite suppressant. The active ingredient within Phentermine is the generic drug phentermine. Phentermine is combined with a resin to create slow release which prolongs the effects of Phentermine.

What does Phentermine look like?

Phentermine capsules are available in 30mg in packs of 30 capsules.

What is Phentermine. prescribed for?

Phentermine is an appetite suppressant and has successfully been helping people lose weight since it was released onto the market. It is designed to be used in combination with a healthy diet and regular exercise.

Who should Phentermine be prescribed for?

Phentermine is only recommended for use among patients who are medically classed as heavily overweight or obese. Only people with a BMI (Body Mass Index) greater than 27+ and who suffer from a related illness such as high cholesterol, high blood pressure or diabetes are normally considered as suitable candidates for the drug.

Phentermine is not recommended for:

  • Children of 18 years or younger
  • The elderly

How does Phentermine work?

Phentermine is an appetite suppressant. Hunger cravings are reduced as the active chemical ingredient in Phentermine effects the parts of the central nervous system. The active ingredient in Phentermine is phentermine. Phentermine is chemically similar to amphetamine and increased energy levels are common among patients.

It is recommended that Phentermine be taken as an accompaniment to a healthy diet and regular exercise.

Phentermine side effects

Side effects of Phentermine can include:


Excess energy




Difficulty in breathing

Light headedness


Ankle and extremity Swelling

Increase in blood pressure



Dryness of the mouth

Unpleasant taste

Diarrhea, Constipation


Changes in sex drive

If used incorrectly or for excessive lengths of time, Phentermine can be habit forming. If over used or abused Phentermine patients can form a habit of perceived dependency. Phentermine should not be taken for a longer period than prescribed by your doctor. Phentermine should not be taken by anyone other than by the person it was prescribed for.

Phentermine dosages

Phentermine capsules should be taken once daily, either before breakfast or within 2 hours of eating breakfast. It is advised to take Phentermine early in the day as it known to cause insomnia and increased energy levels.

Phentermine capsules should be swallowed whole with plenty of water.

Phentermine is not recommended for patients of 18 years old or younger. It is not recommend that the elderly be prescribed Phentermine .

What precautions should be taken before using Phentermine?

Inform your Doctor of the following:

  • Any allergies that you may have, especially to if you have a known allergy to phentermine.
  • Any other medicines that you are taking at the time (both prescription and over the counter)
  • If your medical history includes high blood pressure, a heart condition, arteriosclerosis, overactive thyroid, diabetes, glaucoma or drug abuse.
  • If you know or suspect that you are pregnant or plan to become pregnant. If you become pregnant while taking Phentermine tell your doctor.
  • If you are breastfeeding a child.
  • If you are prone to agitated states.

Over dosage

Overdoses of Phentermine can have serious consequences, if quantities are high enough this can include death. If an overdose is suspected seek medical help immediately.

Symptoms of overdosage can include: excess energy, tremor, hyperreflexia, increased breathing rate, confusion, assaultiveness, hallucinations, panic, excess fatigue, depression, arrhythmia, hypertension or hypotension, circulatory collapse, vomiting, diarrhea, abdominal cramps.

Fatal poisoning usually terminates in convulsions and coma.